Friday, January 06, 2017

Symptoms of aflatoxins poisoning

Aflatoxin, one of the most familiar mycotoxins associated with foods, are secondary metabolites produced by certain strains of Aspergillus (A. flavus and A. parasiticus).

The major aflatoxins of concern to humans are aflatoxins B1, B2, G1 and G2.

Symptoms are:
Loss of appetite
Nausea, vomiting, and abdominal pain
High fever Rapidly progressing jaundice
Convulsions
Pulmonary edema, fluid buildup (edema) in the lungs ('pulmon-')
Cerebral edema, fluid buildup in the brain ('cerebro-')
Blood abnormalities, such as an increased risk of bleeding out
Swollen and severe damage to the liver
Bloody or blackened stools
Damage to the kidneys and heart
Death

Aflatoxin causes severe hepatocellular necrosis (acute liver failure) within 72 hours. Outbreaks of aflatoxin poisoning are very rare in developed countries but do occasionally occur worldwide.
Symptoms of aflatoxins poisoning

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